Clinical Research Abstracts

Waterpik® Water Flossers Significantly Reduce Plaque Biofilm, Gingivitis, and Bleeding for Patients with Diabetes

Comparative Evaluation of Adjunctive Oral Irrigation in Diabetes

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To compare the addition of the Waterpik® Water Flosser with the Pik Pocket subgingival irrigation tip to routine oral hygiene on the periodontal health of people with diabetes.


52 subjects with periodontal disease and either type 1 or type 2 diabetes participated in this 3-month randomized clinical trial. All subjects had scaling and root planing at baseline then were assigned to either add a Waterpik® Water Flosser with the Pik Pocket Tip twice daily to their oral hygiene routine or to continue practicing their regular oral hygiene routine. Periodontal health was measured via clinical and metabolic parameters.


Adding the Waterpik® Water Flosser was superior to normal oral hygiene in reducing the traditional measures of periodontal disease: plaque biofilm, gingivitis, and bleeding on probing. The Water Flosser also reduced the serum levels of proinflammatory cytokines IL-1B and PGE2, as well as the level of reactive oxygen species, a bacteria and host-mediated pathway for tissue destruction implicated in the pathogenesis of over 100 conditions.


The Waterpik® Water Flosser provided significant periodontal health benefits, both clinically and biologically to people with diabetes.